Drug Discovery
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chittii
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#1
17-03-2010, 02:32 PM


Please provide the documentation for the "Drug discovery".
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project topics
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#2
24-11-2010, 03:58 PM

Drug discovery is the process by which drugs are discovered or designed in the field of medicine, biotechnology and pharmacology ,In the past most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery. A new approach has been to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on this knowledge.
The process of drug discovery involves the identification of candidates, synthesis, characterization, screening, and assays for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials.The process of finding a new drug against a chosen target for a particular disease usually involves high-throughput screening (HTS), wherein large libraries of chemicals are tested for their ability to modify the target.


referencing:
en.wikipediawiki/Drug_discovery
naturenrd/journal/v7/n7/abs/nrd2290.html
Use Search at http://topicideas.net/search.php wisely To Get Information About Project Topic and Seminar ideas with report/source code along pdf and ppt presenaion
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#3
17-05-2012, 01:59 PM

Drug Discovery


Project Objectives:
1. Discover and utilize a variety of resources to research biological scientific information.
2. Learn about the drug discovery process.
3. Give a short scientific presentation.
4. Write a research paper.

Project Summary:
1. Read the Drug Discovery Research Project instructions carefully, in addition to both the grading rubrics before you begin. This will give you an excellent idea of expectation.
2. Read Chapter 3 “The Lifecycle of Pharmaceutical Products”, Seidman & Moore, 2nd Ed.
3. Watch a video on the drug discovery process (in class and posted on Blackboard).
4. Pick a FDA-approved and currently available drug to research. Pick a drug that has been developed within the last 20 years. You will need clinical data! You may not use the examples utilized to outline the drug discovery process described in Chapter 3 or these past examples: Actonel, Advair, Ampyra, Chantix, Omeprazole, Requip XL, Xanax, Nystatin, Ciprofloxacin, Lexapro, Cymbalta, Insulin, Human Growth Hormone, Tissue Plasminogen Activator, Taxol, Gleevec, Herceptin, Lipitor, Prozac, any HIV drug.
5. Only one student is permitted per drug, so get your choice in early! Topic choice is due July 12th.
4. Utilizing your textbook, the library, news articles, scientific journals and internet resources, find information on how this drug was discovered and developed. Remember to document ALL sources! You should start here:
a. Describe the chemistry and biochemistry of the drug. What is it and how does it work biologically?
b. Describe the drug discovery process for this drug:
i. Research and Discovery – Who discovered it? How?
ii. Preclinical Development – What types of studies were done prior to clinical trials?
iii. Clinical Development (phase I, II, III trials)
iv. Surveillance (Post-Approval activities)
c. Were there any problems with its testing at any place in the development process?
d. Discuss its track record on the market (post-approval surveillance).
6. Develop a 15-20 minute Power Point presentation on your research. The presentation should follow the key points listed in the rubric. Use the guide of approximately 1 slide/minute (depending on the slide). If you do not have Power Point available at home, it is available at the ACC computer centers (library) and the learning center. The learning center will also assist you with using the program.
7. You are required to upload your PowerPoint presentation the day BEFORE the presentation into “Dropbox” on Blackboard (before Monday Aug 9th). That way you are ensured to have an emergency working copy the day of the presentations, as well as a copy uploaded for grading. If you make any changes to your presentation, you are required to upload the best and most recent copy for grading at the end of class.
8. Write a paper summarizing the drug development process for the drug you have chosen. Use the Modern Language Association (MLA) format. Purdue’s formatting and style guide is posted on Blackboard. You may use that or any other MLA format guide. Reference the one you use! The paper should follow the key points listed in the rubric.
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hillyjay
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#4
18-05-2012, 11:20 AM

Interesting thread. This is a great resource. I know I will learn so much from here.
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